Spravato® (Esketamine) Treatment
Breakthrough Depression Treatment
FDA-approved Spravato® (esketamine) nasal spray for depression-resistant treatment. Rapid relief often within hours, administered under clinical supervision with comprehensive support.
FDA-Approved Treatment
What is Spravato®?
Spravato® is a nasal form of esketamine, a derivative of ketamine, approved by the US Food and Drug Administration for treatment-resistant depression.
- Rapid relief often within hours of treatment
- More potent than ketamine, requiring lower doses
- Potentially fewer side effects than alternatives
- Must be used with traditional oral antidepressants.
Unique Mechanism of Action
Unlike conventional antidepressants that act on serotonin or norepinephine, esketamine increases the glutamate levels in the brain, stimulating many brain cells at once.
Treatment Process
How Spravato® Works
Clinical Administration
Patients self-administer doses under clinician supervision at our clinic. Treatment requires about 2 hours of observation
Treatment Schedule
Typically twice weekly for the first month, then weekly or every two weeks for maintenance. Schedule adjusted based on individual response.
Rapid Action
Stimulates glutamate activity, leading to faster relief of depressive symptoms and reductions in suicidal thoughts within hours.
Treatment Timeline
Week 1-4
Induction Phase
Twice weekly treatments with close monitoring
Week 5-8
Optimization
Weekly treatments, assess response and adjust
Week 9+
Maintenance
Every 1-2 weeks based on individual needs.
on-going
Long-term
Continued monitoring and support therapy.
Treatment Eligibility
What Can Benefit from Spravato®?
Spravato® is specifically designed for adults with treatment-resistant depression who have not found sufficient relief with traditional treatments.
Treatment-Resistant Depression
Adults who have tried at least two other antidepressants without sufficient relief.
Combination Therapy
Must be combined with a traditional oral antidepressant medication.
Comprehensive Support
Used alongside psychotherapy or other mental health support services.
Important Considerations
Spravato® requires careful evaluation and ongoing monitoring. Our clinicians assess your treatment history, current medical conditions, and overall health to determine if this treatment is appropriate for you.
Patients should discuss all risks and benefits with their provider and adhere to monitoring requirements.
Ready to Begin Your Journey?
Take the first step toward comprehensive mental health care with our specialized treatment programs.
Call Us
(509) 381-6035
support@oasishealthservices.com
Flexible Appointments
Telehealth & in-person options